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Table 1 Demographic data of 258 evaluated hormone receptor-positive patients

From: HER4 expression in estrogen receptor-positive breast cancer is associated with decreased sensitivity to tamoxifen treatment and reduced overall survival of postmenopausal women

Clinicopathological parameter

Premenopausal (n = 67)

Postmenopausal (n = 191)

n

%

n

%

Tumor stage

 I

32

48

111

58

 II

28

42

67

35

 III

4

6

8

4

 IV

0

0

0

0

 Unknown

3

4

5

3

Subtype

 Invasive ductal

56

84

151

79

 Invasive lobular

7

10

24

13

 Others

4

6

16

8

Grading

 1

5

7

25

13

 2

44

66

110

58

 3

17

25

52

27

 Unknown

1

1

4

2

Lymph node status

 0

30

45

116

61

 1

19

28

52

27

 2

10

15

13

7

 3

6

9

6

3

 Unknown

2

3

4

2

Endocrine treatment

 Tamoxifen

43

64

66

35

 Aromatase inhibitor

24

36

125

65

Surgery

 Mastectomy

27

40

51

27

 Breast-conserving therapy

40

60

140

73

Radiation

 Yes

50

75

151

79

 No

7

10

23

12

 Unknown

10

15

17

9

Cytotoxicity treatment

 Yes

56

84

85

44

 No

1

1

3

2

 Unknown

10

15

103

54