Fig. 4

Chronological steps of lymph node metastasis (H&E stain). a An uninvolved axillary LN with no evidence of tumour cells (0.7×). b Partial colonisation of a LN with significant amount of residual uninvolved LN tissue (black arrowhead) and two nodules of metastasis (black arrows) are depicted (0.5×). Inset shows tumour cells mixed with background immune cells (20×). c A lymph node with near total replacement of normal lymph nodal tissue (1×). The inset displays a higher power magnification of tumour cells (10×). All images were captured by Nanozoomer and viewed in NDP.view2 software (Hamamatsu)