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Fig. 4 | Breast Cancer Research

Fig. 4

From: Induction of cell cycle arrest and inflammatory genes by combined treatment with epigenetic, differentiating, and chemotherapeutic agents in triple-negative breast cancer

Fig. 4

ED and EAD induce expression of proinflammatory genes. qRT-PCR of (a) genes associated with immune cell activation and recruitment, (b) cancer testis antigens (CTA), and (c) immune checkpoints. t test used to compare mean level of expression (± SEM) in qRT-PCR after RPL39 normalization. *Compared to entinostat; #compared to doxorubicin: */#p < 0.05, **/##p < 0.01, ***p < 0.001. d Western blot analysis of GITRL and IL13RA2 in MDA-MB-231 cells treated as described in text. Loading control: β-actin. E entinostat, A all-trans retinoic acid, D doxorubicin, Veh vehicle, ns not significant

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Breast Cancer Research

ISSN: 1465-542X

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