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Table 1 The influence of statin therapy on cancer incidence, recurrence, and mortality

From: Statin drugs to reduce breast cancer recurrence and mortality

Cancer type

The effect of statin therapy on cancer

Incidence

Recurrence

Mortality

Breast

↔ (Hydrophilic statins)

↓ (All or lipophilic statins)

↔ (Hydrophilic statins)

↓ (All or lipophilic statins)

Prostate

↔ (Radical prostatectomy)

↓ (Radiotherapy)

↓ (All, lipophilic, or hydrophilic statins)

Lung

↔ (Pravastatin)

↓ (All statins)

↔ (Pravastatin)

↓ (All statins)

Colorectal

↓ (All statins)

↓ (All statins)

Primary liver

↓ (All Statins)

↓ (All statins or pravastatin)

↓ (All statins or pravastatin)

  1. The influence of statins on cancer incidence, recurrence, and mortality for breast, prostate, lung, colorectal, and primary liver cancer. ↔ = no effect, ↓ = reduction. All statins, hydrophilic statins, and lipophilic statins refer to studies that were conducted examining patients taking any statin, any hydrophilic statin, or any lipophilic statin, respectively