Fig. 1From: Statin drugs to reduce breast cancer recurrence and mortalityThe cholesterol biosynthesis pathway. Statins block HMG-CoA reductase (HMGCR, shown in blue) to shut down the cholesterol biosynthetic pathway. In addition to cholesterol, other downstream mediators are affected, such as farnesyl pyrophosphate (FPP) and geranylgeranyl pyrophosphate (GGPP)Back to article page