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Table 2 Association between the general cognitive factor and history of cancer and inflammatory markers and history of cancer

From: Inflammation markers and cognitive performance in breast cancer survivors 20 years after completion of chemotherapy: a cohort study

Outcome

Model I

Model II

Mean difference (95% CI)

Mean difference (95% CI)

Inflammatory marker*

 Log GLR

0.30 (0.24 to 0.36)

0.31 (0.24 to 0.37)

 Log PLR

0.16 (0.10 to 0.21)

0.14 (0.09 to 0.19)

 Log SII

0.30 (0.23 to 0.38)

0.31 (0.24 to 0.39)

Cognition†

 General cognitive factor

−0.18 (−0.34 to −0.03)

−0.21 (−0.35 to −0.06)

  1. Abbreviations: CI confidence interval, GLR granulocyte-to-lymphocyte ratio, PLR platelet-to-lymphocyte ratio, SII systemic immune-inflammation index
  2. Model I is a linear regression of the general cognitive factor or log-transformed inflammatory markers on cancer status adjusted for age and education. Model II is as model I plus adjustment for smoking status, body mass index, diabetes mellitus, history of stroke, history of myocardial infarction, and Center for Epidemiologic Studies Depression Scale (CES-D) sum-score
  3. *Mean difference in general cognitive factor between breast cancer survivors and non-exposed participants
  4. †Mean difference in inflammatory markers between breast cancer survivors and non-exposed participants
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Breast Cancer Research

ISSN: 1465-542X

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