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Table 1 Demographics and characteristics of breast cancer survivors and non-exposed participants

From: Inflammation markers and cognitive performance in breast cancer survivors 20 years after completion of chemotherapy: a cohort study

Characteristic

Breast cancer survivors

(n = 166)

Non-exposed participants

(n = 1344)

P

Age in years, mean (SD)

64.0 (6.7)

57.9 (5.2)

<0.001

Education level, no. (%)

  

<0.001

 Primary

14 (8.4)

158 (11.8)

 

 Low

59 (35.5)

616 (45.8)

 

 Intermediate

33 (19.9)

287 (21.4)

 

 High

60 (36.1)

283 (21.1)

 

Body mass index in kg/m2, mean (SD)

26.9 (4.6)

27.4 (4.8)

0.181

Smoking status, no. (%)

  

<0.001

 Current

16 (9.6)

295 (21.9)

 

 Former

93 (56.0)

574 (42.7)

 

Diabetes mellitus, no. (%)

14 (8.4)

54 (4.0)

0.008

History of stroke, no. (%)

1 (0.6)

19 (1.4)

0.715

History of myocardial infarction, no. (%)

6 (3.6)

11 (0.8)

0.001

CES-D sum-score, mean (SD)

14.5 (3.6)

14.8 (4.4)

0.450

General cognitive factor, mean (SD)

−0.39 (1.14)

0.05 (0.97)

<0.001

Inflammatory markers, median (IQR)

 GLR

2.06 (1.67–2.66)

1.52 (1.20–1.92)

<0.001

 PLR

145 (119–176)

124 (102–151)

<0.001

 SII

618 (469–796)

443 (328–595)

<0.001

Age at breast cancer diagnosis in years, mean (SD)

42.9 (5.6)

  

Time since breast cancer diagnosis, mean (SD)

21.0 (4.5)

  
  1. Abbreviations: CES-D Center for Epidemiologic Studies Depression Scale, GLR granulocyte-to-lymphocyte ratio, IQR interquartile range, PLR platelet-to-lymphocyte ratio, SD standard deviation, SII systemic immune-inflammation index