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Fig. 7 | Breast Cancer Research

Fig. 7

From: Sulfatide decreases the resistance to stress-induced apoptosis and increases P-selectin-mediated adhesion: a two-edged sword in breast cancer progression

Fig. 7

Expression of GAL3ST1 in IDC tissue specimens. Immunohistochemical staining of breast cancer tumours representing malignancy grades: (a) G1 and (b) G3 (magnification 400×). c Reaction intensities with anti-GAL3ST1 antibody calculated on basis of semi-quantitative IRS scale of Remmele and Stegner [21] and represented as mean. **p < 0.01 for G1 grade breast tumours compared to G3 grade breast tumours (Mann–Whitney U test). d Mantel–Cox analysis distinguished breast cancer patients who were GAL3ST1-positive and GAL3ST1-negative. Patients expressing GAL3ST1 had longer overall survival (*p < 0.05). e Overall survival of GAL3ST1-positive and GAL3ST1-negative breast cancer patients who received chemotherapy (Mantel–Cox analysis, p = 0.1206). Gal3ST1 galactosylceramide sulfotransferase, IRS semi-quantitative immune reactive score, SD standard deviation

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Breast Cancer Research

ISSN: 1465-542X

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