Fig. 3

Xenograft tumour growth of MDA.SUL cells with overexpression of GAL3ST1 and control MDA.C cells. a Tumour growth recorded once a week by measuring diameter with a calliper. Data shown as mean tumour volume for group of mice (n   =  8 for MDA.SUL cells and n = 9 for MDA.C cells) ± SE at each indicated time point. Data analysed using Bonferroni multiple comparison test. ^*p < 0.05, ^**p < 0.01, ^***p < 0.001. b TUNEL assay after subcutaneous implantation of MDA.SUL (I) and MDA.C (II) cells. Arrows indicate the apoptotic cells. Numbers of apoptotic cells in MDA.SUL and MDA.C tumours compared (III) by Mann–Whitney U test (p = 0.0494). TUNEL terminal transferase dUTP nick end labelling