Fig. 4
From: Disrupted circadian clocks and altered tissue mechanics in primary human breast tumours
Micromechanical stiffness of periductal stroma. a Mean reduced modulus for periductal regions of the stroma in normal (blue) versus tumour (red) tissue sections from five patients. The regions analysed are shown in Additional file 6: Figure S6. b Mean reduced modulus for periductal regions of the stroma in tumour tissue compared with normal breast tissue (in all five patients assessed). Tumour periductal stroma (reduced modulus = 1.21 MPa) was significantly stiffer than normal periductal stroma (reduced modulus = 0.90 MPa, p < 0.0001, n = 5)