Table 4 Associationa between road traffic noise Lden and incidence of breast cancer by combination of estrogen and progesterone receptor status in 22,466 nurses from Danish Nurse Cohort
From: Long-term exposure to road traffic noise and incidence of breast cancer: a cohort study
ER+/PR+ | ER+/PR- | ER-/PR+ | ER-/PR- | |||||
|---|---|---|---|---|---|---|---|---|
Number of cases | HR (95% CI) | Number of cases | HR (95% CI) | Number of cases | HR (95% CI) | Number of cases | HR (95% CI) | |
24 years preceding diagnosis | ||||||||
Linear per 10 dB | 384 | 1.21 (1.02–1.42)* | 110 | 1.33 (0.97–1.82) | 9 | 1.14 (0.33–3.87) | 108 | 0.92 (0.68–1.25) |
Low < 48 dB | 45 | 1.00 | 13 | 1.00 | 0 | 1.00 | 22 | 1.00 |
Medium 48–58 dB | 226 | 1.49 (1.07–2.07)* | 64 | 1.45 (0.78–2.69) | 5 | – | 57 | 0.73 (0.43–1.22) |
High > 58 dB | 113 | 1.61 (1.11–2.34)* | 33 | 1.51 (0.75–3.03) | 4 | – | 29 | 0.88 (0.48–1.62) |
10 years preceding diagnosis | ||||||||
Linear per 10 dB | 384 | 1.20 (1.03–1.40)* | 110 | 1.30 (0.98–1.74) | 9 | 1.22 (0.40–3.72) | 108 | 0.98 (0.74–1.29) |
Low < 48 dB | 51 | 1.00 | 13 | 1.00 | 0 | 1.00 | 23 | 1.00 |
Medium 48–58 dB | 218 | 1.53 (1.11–2.09)* | 61 | 1.65 (0.89–3.06) | 5 | – | 59 | 0.85 (0.51–1.40) |
High > 58 dB | 115 | 1.61 (1.13–2.29)* | 36 | 1.83 (0.92–3.62) | 4 | – | 26 | 0.79 (0.43–1.46) |
1 year preceding diagnosis | ||||||||
Linear per 10 dB | 384 | 1.21 (1.05–1.39)* | 110 | 1.07 (0.83–1.40) | 8 | 1.15 (0.39–3.40) | 108 | 1.10 (0.84–1.43) |
Low < 48 dB | 58 | 1.00 | 19 | 1.00 | 1 | 1.00 | 20 | 1.00 |
Medium 48–58 dB | 212 | 1.42 (1.05–1.92)* | 56 | 1.09 (0.64–1.87) | 4 | 1.02 (0.11–9.59) | 61 | 1.14 (0.67–1.92) |
High > 58 dB | 114 | 1.53 (1.09–2.15)* | 35 | 1.27 (0.69–2.34) | 3 | 1.35 (0.13–14.4) | 27 | 1.09 (0.59–2.03) |