Table 3 Associationa between road traffic noise Lden and incidence of breast cancer by ER and PR status in 22,466 nurses with estrogen and progesterone hormone receptor status from the Danish Nurse Cohort
From: Long-term exposure to road traffic noise and incidence of breast cancer: a cohort study
Breast cancer type by ER status | Breast cancer type by PR status | |||||||
|---|---|---|---|---|---|---|---|---|
Number of cases | ER+ | Number of cases | ER- | Number of cases | PR+ | Number of cases | PR- | |
HR (95% CI) | HR (95% CI) | HR (95% CI) | HR (95% CI) | |||||
24 years preceding diagnosis | ||||||||
Linear per 10 dB | 494 | 1.23 (1.06–1.43)* | 117 | 0.93 (0.70–1.25) | 393 | 1.21 (1.02–1.42)* | 218 | 1.10 (0.89–1.37) |
Low < 48 dB | 58 | 1.00 | 22 | 1.00 | 45 | 1.00 | 35 | 1.00 |
Medium 48–58 dB | 290 | 1.48 (1.10–1.98)* | 62 | 0.77 (0.46–1.28) | 231 | 1.51 (1.08–2.10)* | 121 | 0.99 (0.67–1.47) |
High > 58 dB | 146 | 1.59 (1.14–2.20)* | 33 | 0.97 (0.54–1.75) | 117 | 1.66 (1.14–2.40)* | 62 | 1.11 (0.70–1.75) |
10 years preceding diagnosis | ||||||||
Linear per 10 dB | 494 | 1.22 (1.07–1.40)* | 117 | 1.00 (0.76–1.30) | 393 | 1.20 (1.03–1.40)* | 218 | 1.13 (0.92–1.37) |
Low < 48 dB | 64 | 1.00 | 23 | 1.00 | 51 | 1.00 | 36 | 1.00 |
Medium 48–58 dB | 279 | 1.55 (1.17–2.05)* | 64 | 0.90 (0.54–1.48) | 223 | 1.55 (1.13–2.12)* | 120 | 1.13 (0.77–1.67) |
High > 58 dB | 151 | 1.65 (1.20–2.26)* | 30 | 0.89 (0.49–1.61) | 119 | 1.65 (1.16–2.35)* | 62 | 1.16 (0.74–1.81) |
1 year at the year of diagnosis | ||||||||
Linear per 10 dB | 494 | 1.18 (1.04–1.33)* | 116 | 1.10 (0.85–1.42) | 392 | 1.21 (1.05–1.39)* | 218 | 1.08 (0.90–1.31) |
Low < 48 dB | 77 | 1.00 | 21 | 1.00 | 59 | 1.00 | 39 | 1.00 |
Medium 48–58 dB | 268 | 1.34 (1.03–1.74)* | 65 | 1.13 (0.68–1.89) | 216 | 1.42 (1.05–1.91)* | 117 | 1.11 (0.76–1.62) |
High > 58 dB | 149 | 1.47 (1.09–1.98)* | 30 | 1.12 (0.61–2.03) | 117 | 1.53 (1.09–2.15)* | 62 | 1.18 (0.76–1.82) |