Fig. 3

Collagen XIII enhances cancer cell migration and invasion. a Phase images (left) and quantification data (right) showing invasion of control and Col13^−/− MDA-MB-231 cells in the Transwell analysis. Data are presented as the mean ± s.e.m.; n = 3; ** p < 0.01. Scale bar: 100 μm. b Quantification of velocity and path length of control and Col13^−/− MDA-MB-231 cells in the single cell migration analysis (Control, n = 22; clone25, n = 30; clone 28, n = 65); * p < 0.05. c Phase images (left) and quantification data (right) showing the invasion of control and Col13-expressing MCF-10A cells in Transwell experiments; n = 3; * p < 0.05. Scale bar: 100 μm. d Quantification of velocity and path length of control and Col13-expressing MCF-10A cells in the single cell migration analysis; n = 25; *** p < 0.001