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Table 2 Population and breast cancer characteristics in the cohort

From: The added value of mammography in different age-groups of women with and without BRCA mutation screened with breast MRI

  Age < 40 years Age 40–50 years Age 50–60 years Age ≥ 60 years Overall p valuea
Women (N)
BRCA 388 258 182 75 903 <0.001
 Others 329 504 482 273 1588 0.014
 Overall 717 762 664 348 2491 <0.001
Exams (N)
BRCA 1113 737 568 190 2608 <0.001
 Others 716 1313 1265 651 3945 0.046
 Overall 1829 2050 1833 841 6553 <0.001
BC (N)
 Mammography 13 13 25 15 66 0.253
 Mammography only 1 2 8 2 13 0.202
 MRI 25 30 37 20 112 0.697
 MRI only 13 19 20 7 59 0.254
 Overall 26 32 45 22 125 0.963
Invasive tumor (N)
 Mammography 13 9 16 12 50 0.771
 Mammography only 1 0 4 0 5 0.822
 MRI 24 25 30 18 97 0.496
 MRI only 12 16 18 6 52 0.253
 Overall 25 25 34 18 102 0.540
DCIS (N)
 Mammography 0 4 9 3 16 0.073
 Mammography only 0 2 5 1 8 0.281
 MRI 1 5 7 2 15 0.036
 MRI only 1 3 2 1 7 0.848
 Overall 1 7 11 4 23 0.164
Tumor grade of all cancers (invasive and in situ) (N)
 Grade 1
  Mammography 1 1 4 1 7 0.536
  Mammography only 0 0 1 0 1 0.655
  MRI 3 4 5 5 17 0.384
  MRI only 2 3 2 4 11 0.442
 Grade 2
  Mammography 1 5 7 4 17 0.171
  Mammography only 0 1 2 1 4 0.317
  MRI 3 10 17 6 36 0.170
  MRI only 2 6 12 3 23 0.335
 Grade 3
  Mammography 11 7 11 6 35 0.339
  Mammography only 1 1 2 1 5 0.822
  MRI 17 15 15 5 52 0.010
  MRI only 7 9 6 0 22 0.009
 Missing 2 1 3 4 10 0.197
FPR (N)
 Mammography 63 75 55 22 215 <0.001
 Mammography only 22 38 28 15 103 0.115
 MRI 159 143 72 25 399 <0.001
 MRI only 118 106 45 18 287 <0.001
 Overall 181 181 100 40 502 <0.001
FPB (N)
 Mammography 35 46 32 9 122 <0.001
 Mammography only 6 15 11 3 35 0.258
 MRI 114 113 51 18 296 <0.001
 MRI only 85 82 30 12 209 <0.001
 Overall 120 128 62 21 331 <0.001
  1. BC breast cancer (invasive cancer and ductal carcinoma in situ (DCIS)), MRI magnetic resonance imaging, FPR false positive recall, FPB false positive biopsy
  2. aChi-square test for trend was performed for the fraction of the overall population