From: Thyroid hormones and breast cancer association according to menopausal status and body mass index
Premenopausal women, n = 306 | Postmenopausal women, n = 1036 | |||||||
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Cases, n = 147 | Controls, n = 159 | Cases, n = 498 | Controls, n = 538 | |||||
Median | Interquartile range | Median | Interquartile range | Median | Interquartile range | Median | Interquartile range | |
Thyroid function parameters | ||||||||
Total triiodotyronine (TT3) nmol/La | 1.6 | 1.3–1.9 | 2.4 | 1.9–2.8 | 1.7 | 1.4–2.1 | 2.6 | 2.1–3.0 |
Mean (SD) | 1.7 | 0.5 | 2.4 | 0.6 | 1.8 | 0.7 | 2.6 | 0.6 |
Total thyroxin (TT4) nmol/La | 103.4 | 87.4–123.1 | 93.1 | 83.7–109.7 | 104.6 | 89.8–122.3 | 96.7 | 84.4–112.2 |
Mean (SD) | 107.3 | 27.3 | 97.2 | 22 | 108.6 | 29.5 | 100.5 | 25.7 |
TSH μUI/mLa | 1.6 | 1.1–2.1 | 1.7 | 1.1–2.3 | 1.8 | 1.1–2.8 | 1.8 | 1.1–2.9 |
Mean (SD) | 1.8 | 1.4 | 2.3 | 3.3 | 2.9 | 9.6 | 2.9 | 6.8 |
Thyroglobulin ng/mLa | 6.4 | 4.0–10.2 | 7.1 | 4.5–12.2 | 7.4 | 3.9–14.5 | 7.4 | 4.0–14.5 |
Mean (SD) | 8.9 | 9.3 | 9.9 | 10.9 | 17.8 | 70.1 | 15.9 | 47.1 |
Anti-peroxidase antibodies UI/mLb | 0.1 | 0.5–2.5 | 1.10 | 0.6–3.1 | 1.1 | 0.6–3.9 | 1.1 | 0.6–3.5 |
Mean (SD) | 46.4 | 266.2 | 222.3 | 1373.8 | 111.1 | 444.6 | 95.0 | 346.3 |
Anti-thyroglobulin antibodiesb,c | ||||||||
Negative | 73 | (49.7) | 59 | (37.1) | 135 | (27.1) | 133 | (24.7) |
Positive | 71 | (48.3) | 100 | (62.9) | 221 | (44.4) | 240 | (44.6) |
Median UI/mL (interquartile range)d | 0.9 | 0.3–3.1 | 1.0 | 0.04–3.0 | 1.0 | 0.3–4.6 | 0.8 | 0.4–2.8 |
Mean (SD)d | 17.7 | 106.4 | 4.7 | 9.8 | 23.1 | 165.1 | 14.4 | 102.4 |