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Table 2 Thyroid function parameters of study participants by menopausal status in the CAMA study, Mexico, 2004–2007

From: Thyroid hormones and breast cancer association according to menopausal status and body mass index

  Premenopausal women, n = 306 Postmenopausal women, n = 1036
Cases, n = 147 Controls, n = 159 Cases, n = 498 Controls, n = 538
Median Interquartile range Median Interquartile range Median Interquartile range Median Interquartile range
Thyroid function parameters
 Total triiodotyronine (TT3) nmol/La 1.6 1.3–1.9 2.4 1.9–2.8 1.7 1.4–2.1 2.6 2.1–3.0
  Mean (SD) 1.7 0.5 2.4 0.6 1.8 0.7 2.6 0.6
 Total thyroxin (TT4) nmol/La 103.4 87.4–123.1 93.1 83.7–109.7 104.6 89.8–122.3 96.7 84.4–112.2
  Mean (SD) 107.3 27.3 97.2 22 108.6 29.5 100.5 25.7
 TSH μUI/mLa 1.6 1.1–2.1 1.7 1.1–2.3 1.8 1.1–2.8 1.8 1.1–2.9
  Mean (SD) 1.8 1.4 2.3 3.3 2.9 9.6 2.9 6.8
 Thyroglobulin ng/mLa 6.4 4.0–10.2 7.1 4.5–12.2 7.4 3.9–14.5 7.4 4.0–14.5
  Mean (SD) 8.9 9.3 9.9 10.9 17.8 70.1 15.9 47.1
 Anti-peroxidase antibodies UI/mLb 0.1 0.5–2.5 1.10 0.6–3.1 1.1 0.6–3.9 1.1 0.6–3.5
  Mean (SD) 46.4 266.2 222.3 1373.8 111.1 444.6 95.0 346.3
 Anti-thyroglobulin antibodiesb,c
  Negative 73 (49.7) 59 (37.1) 135 (27.1) 133 (24.7)
  Positive 71 (48.3) 100 (62.9) 221 (44.4) 240 (44.6)
   Median UI/mL (interquartile range)d 0.9 0.3–3.1 1.0 0.04–3.0 1.0 0.3–4.6 0.8 0.4–2.8
Mean (SD)d 17.7 106.4 4.7 9.8 23.1 165.1 14.4 102.4
  1. CAMA study Risk factors for breast cancer in Mexico: mammographic patterns, C peptide, and growth factors, a multicenter study, TSH thyroid stimulating hormone
  2. aThere are no missing values for TT3, TT4, TSH and thyroglobulin
  3. bResults correspond to 147 cases and 159 controls (premenopausal women), respectively; and to 356 cases and 373 controls (postmenopausal)
  4. cNumber and (percentage) of women with negative/positive anti-thyroglobulin antibodies
  5. dThe values correspond to women with positive results for anti-thyroglobulin antibodies