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Table 1 Characteristics of study participants by menopausal status in the CAMA study, Mexico, 2004–2007

From: Thyroid hormones and breast cancer association according to menopausal status and body mass index

  Premenopausal women, n = 306 Postmenopausal women, n = 1036
Cases, n = 147 Controls, n = 159 Cases, n = 498 Controls, n = 538
Number (%)a Number (%)a Number (%)a Number (%)a
Sociodemographic
 Age (years)b 44.1 38.6–47.3 44.1 40.6–47.8 58.0 52.9–64.3 57.4 52.3–62.1
 Wealth index
  Low 52 (35.4) 45 (28.3) 155 (31.1) 199 (37.0)
  Medium 38 (25.9) 49 (30.8) 125 (25.1) 187 (34.8)
  High 57 (38.8) 65 (40.9) 218 (43.8) 152 (28.3)
Indigenous ancestry percent
 0–25% 3 (2.0) 4 (2.5) 21 (4.2) 10 (1.9)
 26–50% 38 (25.9) 41 (25.8) 130 (26.1) 125 (23.2)
 51–75% 49 (33.3) 77 (48.4) 188 (37.8) 245 (45.5)
 76–100% 18 (12.2) 33 (20.8) 79 (15.9) 139 (25.8)
Reproductive health
 Time of exposure to endogenous hormones (years)b     34 30–37 34 29–37
 Parity
  None 21 (14.3) 13 (8.2) 62 (12.4) 23 (4.3)
  1–3 93 (63.3) 98 (61.6) 227 (45.6) 209 (38.8)
   ≥ 4 32 (21.8) 47 (29.6) 205 (41.2) 306 (56.9)
 Use of contraception at any point at life
  No 85 (57.8) 86 (54.1) 294 (59.0) 299 (55.6)
  Yes 62 (42.2) 73 (45.9) 202 (40.6) 239 (44.4)
 Use of hormones for menopause for more than 1 month
  No 380 (76.3) 456 (84.8)
  Yes 114 (22.9) 81 (15.1)
 Breastfeeding in monthsb 9 2–25 12 4–34 12 1–42 24 6–57
Anthropometry
 Waist circumference (cm)b,c 93.3 84.8 - 101.5 97.7 92–107.0 97.0 90.3–104.8 99.5 91.65–108.0
 Hip circumference (cm)b,c 103.1 97.2 - 111.0 107.9 102 - 115.7 106.25 100.3–114.6 108.0 101–117.0
 Height (cm)b,c 154.5 150.5 - 158.5 153.8 149.7 - 158.0 151.8 147.3–156.0 150.5 146.7–154.4
 Weight (kg)b,c 65.8 59.5 - 74.2 70.2 64.0–79.6 67.2 60.2–76.6 67.8 60.4–77.4
 Body mass index (weight in kg/height squared)b,c 27.4 24.9–31.5 29.8 27.1–33.4 29.2 26.4–33.2 30.2 27.1–33.8
 Waist-hip ratiob,c 0.90 0.86–0.94 0.91 0.87–0.95 0.91 0.87–0.96 0.91 0.87–0.97
Silhouette trajectory
 Group 1, constantly low 19 (12.9) 28 (17.6) 76 (15.3) 94 (17.5)
 Group 2, constantly mid-range 57 (38.8) 56 (35.2) 199 (40.0) 200 (37.2)
 Group 3, moderate increase 27 (18.4) 32 (20.1) 101 (20.3) 117 (21.7)
 Group 4, Strong increase 41 (27.9) 37 (23.3) 104 (20.9) 113 (21.0)
 Group 5, constantly high 3 (2.0) 6 (3.8) 18 (3.6) 14 (2.6)
Breast pathology
 Personal history of benign breast disease
  No 126 (85.7) 140 (88.1) 425 (85.3) 506 (94.1)
  Yes 20 (13.6) 16 (10.1) 65 (13.1) 27 (5.0)
 Family history of breast cancer (mother, grandmother, and sisters)
  No 137 (93.2) 148 (93.1) 466 (93.6) 525 (97.6)
  Yes 10 (6.8) 11 (6.9) 32 (6.4) 13 (2.4)
Lifestyle
 Hours of moderate-intensity physical activity per weekb,d 9.0 3.5–18.0 12.0 2.0–25.5 5.5 1.0–10.5 12.0 2.0–22.0
 Consumed on average one or more alcoholic drinks a month for a year
  No 108 (73.5) 139 (87.4) 403 (80.9) 472 (87.7)
  Yes 39 (26.5) 18 (11.3) 70 (14.1) 47 (8.7)
 Smoked at least 100 cigarettes in her lifetime
 No 119 (81.0) 113 (71.1) 370 (74.3) 442 (82.2)
 Yes 28 (19.0) 46 (28.9) 128 (25.7) 96 (17.8)
 Daily total consumption of calories (Kcal)b,d 2262.6 1776.1 - 2704.1 1853.0 1514.8–2302.6 2014.9 1631.1–2557.1 1748.5 1396.0–2160.4
Comorbidities
 Diagnosed with diabetes mellitus by a physician
  No 123 (84.4) 130 (82.4) 330 (66.3) 399 (74.2)
  Yes 15 (10.2) 18 (11.3) 126 (25.3) 107 (19.9)
  1. CAMA study Risk factors for breast cancer in Mexico: mammographic patterns, C peptide, and growth factors, a multicenter study
  2. aPercentages do not necessarily add up to 100% due to missing values
  3. bValues correspond to the median and interquartile range
  4. cMissing values in percentage: waist: premenopausal women: cases 0%, controls 3.1%; postmenopausal women: cases 3.8%, controls 1.9%; height: premenopausal women: cases 2%, controls 0%; postmenopausal women: cases 0%, controls 0%; body mass index: premenopausal women: cases 2%, controls 0%; postmenopausal women: cases 0%, controls 0%; waist-to-hip ratio: premenopausal women: cases 2.0%, controls 3.1%; postmenopausal women: cases 3.8%, controls 2.0%
  5. dMissing values: hours of moderate-intensity physical activity per week: premenopausal women: cases 0%, controls 0%; postmenopausal women: cases 0.2%, controls 0%; daily total consumption of calories (Kcal): premenopausal women: cases 10.9%, controls 10.1%; postmenopausal women cases 5.6%, controls 7,6%