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Table 1 Characteristics of study participants by menopausal status in the CAMA study, Mexico, 2004–2007

From: Thyroid hormones and breast cancer association according to menopausal status and body mass index

 

Premenopausal women, n = 306

Postmenopausal women, n = 1036

Cases, n = 147

Controls, n = 159

Cases, n = 498

Controls, n = 538

Number

(%)a

Number

(%)a

Number

(%)a

Number

(%)a

Sociodemographic

 Age (years)b

44.1

38.6–47.3

44.1

40.6–47.8

58.0

52.9–64.3

57.4

52.3–62.1

 Wealth index

  Low

52

(35.4)

45

(28.3)

155

(31.1)

199

(37.0)

  Medium

38

(25.9)

49

(30.8)

125

(25.1)

187

(34.8)

  High

57

(38.8)

65

(40.9)

218

(43.8)

152

(28.3)

Indigenous ancestry percent

 0–25%

3

(2.0)

4

(2.5)

21

(4.2)

10

(1.9)

 26–50%

38

(25.9)

41

(25.8)

130

(26.1)

125

(23.2)

 51–75%

49

(33.3)

77

(48.4)

188

(37.8)

245

(45.5)

 76–100%

18

(12.2)

33

(20.8)

79

(15.9)

139

(25.8)

Reproductive health

 Time of exposure to endogenous hormones (years)b

   

34

30–37

34

29–37

 Parity

  None

21

(14.3)

13

(8.2)

62

(12.4)

23

(4.3)

  1–3

93

(63.3)

98

(61.6)

227

(45.6)

209

(38.8)

   ≥ 4

32

(21.8)

47

(29.6)

205

(41.2)

306

(56.9)

 Use of contraception at any point at life

  No

85

(57.8)

86

(54.1)

294

(59.0)

299

(55.6)

  Yes

62

(42.2)

73

(45.9)

202

(40.6)

239

(44.4)

 Use of hormones for menopause for more than 1 month

  No

380

(76.3)

456

(84.8)

  Yes

114

(22.9)

81

(15.1)

 Breastfeeding in monthsb

9

2–25

12

4–34

12

1–42

24

6–57

Anthropometry

 Waist circumference (cm)b,c

93.3

84.8 - 101.5

97.7

92–107.0

97.0

90.3–104.8

99.5

91.65–108.0

 Hip circumference (cm)b,c

103.1

97.2 - 111.0

107.9

102 - 115.7

106.25

100.3–114.6

108.0

101–117.0

 Height (cm)b,c

154.5

150.5 - 158.5

153.8

149.7 - 158.0

151.8

147.3–156.0

150.5

146.7–154.4

 Weight (kg)b,c

65.8

59.5 - 74.2

70.2

64.0–79.6

67.2

60.2–76.6

67.8

60.4–77.4

 Body mass index (weight in kg/height squared)b,c

27.4

24.9–31.5

29.8

27.1–33.4

29.2

26.4–33.2

30.2

27.1–33.8

 Waist-hip ratiob,c

0.90

0.86–0.94

0.91

0.87–0.95

0.91

0.87–0.96

0.91

0.87–0.97

Silhouette trajectory

 Group 1, constantly low

19

(12.9)

28

(17.6)

76

(15.3)

94

(17.5)

 Group 2, constantly mid-range

57

(38.8)

56

(35.2)

199

(40.0)

200

(37.2)

 Group 3, moderate increase

27

(18.4)

32

(20.1)

101

(20.3)

117

(21.7)

 Group 4, Strong increase

41

(27.9)

37

(23.3)

104

(20.9)

113

(21.0)

 Group 5, constantly high

3

(2.0)

6

(3.8)

18

(3.6)

14

(2.6)

Breast pathology

 Personal history of benign breast disease

  No

126

(85.7)

140

(88.1)

425

(85.3)

506

(94.1)

  Yes

20

(13.6)

16

(10.1)

65

(13.1)

27

(5.0)

 Family history of breast cancer (mother, grandmother, and sisters)

  No

137

(93.2)

148

(93.1)

466

(93.6)

525

(97.6)

  Yes

10

(6.8)

11

(6.9)

32

(6.4)

13

(2.4)

Lifestyle

 Hours of moderate-intensity physical activity per weekb,d

9.0

3.5–18.0

12.0

2.0–25.5

5.5

1.0–10.5

12.0

2.0–22.0

 Consumed on average one or more alcoholic drinks a month for a year

  No

108

(73.5)

139

(87.4)

403

(80.9)

472

(87.7)

  Yes

39

(26.5)

18

(11.3)

70

(14.1)

47

(8.7)

 Smoked at least 100 cigarettes in her lifetime

 No

119

(81.0)

113

(71.1)

370

(74.3)

442

(82.2)

 Yes

28

(19.0)

46

(28.9)

128

(25.7)

96

(17.8)

 Daily total consumption of calories (Kcal)b,d

2262.6

1776.1 - 2704.1

1853.0

1514.8–2302.6

2014.9

1631.1–2557.1

1748.5

1396.0–2160.4

Comorbidities

 Diagnosed with diabetes mellitus by a physician

  No

123

(84.4)

130

(82.4)

330

(66.3)

399

(74.2)

  Yes

15

(10.2)

18

(11.3)

126

(25.3)

107

(19.9)

  1. CAMA study Risk factors for breast cancer in Mexico: mammographic patterns, C peptide, and growth factors, a multicenter study
  2. aPercentages do not necessarily add up to 100% due to missing values
  3. bValues correspond to the median and interquartile range
  4. cMissing values in percentage: waist: premenopausal women: cases 0%, controls 3.1%; postmenopausal women: cases 3.8%, controls 1.9%; height: premenopausal women: cases 2%, controls 0%; postmenopausal women: cases 0%, controls 0%; body mass index: premenopausal women: cases 2%, controls 0%; postmenopausal women: cases 0%, controls 0%; waist-to-hip ratio: premenopausal women: cases 2.0%, controls 3.1%; postmenopausal women: cases 3.8%, controls 2.0%
  5. dMissing values: hours of moderate-intensity physical activity per week: premenopausal women: cases 0%, controls 0%; postmenopausal women: cases 0.2%, controls 0%; daily total consumption of calories (Kcal): premenopausal women: cases 10.9%, controls 10.1%; postmenopausal women cases 5.6%, controls 7,6%