Parameter | Week after 4T1 cancer cell inoculation | |||||
---|---|---|---|---|---|---|
Control | 1st | 2nd | 3rd | 4th | 5th | |
Lung weight (g) | 0.76; 0.70–0.80 (n = 30) | 0.77; 0.70–0.81 (n = 29) | 0.76; 0.72–0.84 (n = 30) | 0.81; 0.76–0.85 (n = 29) | 0.0.82; 0.77–0.91 (n = 30) | 1.7; 1.3–2.22*** (n = 49) |
WBC (K/μl) | 4.20; 3.41–5.22 (n = 35) | 4.70; 4.04–5.28 (n = 21) | 5.55; 4.94–6.21 (n = 23) | 17.02; 11.85–24.78*** (n = 23) | 54.62; 96.18–177.10*** (n = 20) | 257.30; 148.20–317.10*** (n = 36) |
GRA (K/μl) | 1.00; 0.80–1.20 (n = 35) | 1.25; 1.10–1.40 (n = 21) | 1.85; 1.35–2.40* (n = 23) | 11.30; 6.95–16.10*** (n = 23) | 79.00; 42.48–132.80*** (n = 20) | 159.80; 89.25–220.90*** (n = 36) |
LYM (K/μl) | 3.10; 2.50–3.85 (n = 35) | 3.25; 2.75–3.87 (n = 21) | 3.40; 2.80–3.90 (n = 23) | 5.65; 4.15–7.00*** (n = 23) | 18.50; 9.75–24.13*** (n = 20) | 46.90; 25.00–95.00*** (n = 35) |
Spleen weight (g) | 0.10; 0.09–0.11 (n = 20) | 0.10; 0.09–0.11 (n = 30) | 0.12; 0.11–0.13 (n = 30) | 0.24; 0.20–0.32** (n = 30) | 0.54; 0.43–0.68*** (n = 30) | 0.89; 0.79–0.99*** (n = 70) |