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Table 1 Classification and cohort characteristics
| Total sample, n (%) | Mutation carriers, n (%) | Mutation carriers per group, n (%) | |
|---|---|---|---|
| Eeles’ LFL criteria | 48/83 (58%) | 6/10 (60%) | 6/48 (13%) |
| Birch’s LFL criteria | 12/83 (15%) | 1/10 (10%) | 1/12 (8%) |
| Original Chompret criteria | 23/83 (28%) | 3/10 (30%) | 3/23 (13%) |
| Chompret 2008 version criteria | 75/83 (90%) | 10/10 (100%) | 10/75 (13%) |
| Chompret 2009 version criteria | 43/83 (52%) | 6/10 (60%) | 6/43 (14%) |
| Chompret 2015 version criteria | 53/83 (64%) | 5/10 (50%) | 5/53 (9%) |
| Classic LFS criteria | 1/83 (1%) | 0/10 | 0/1 |
| Early-onset BC (i.e., ≤ 34 years) | 50/83 (60%) | 7/10 (70%) | 7/50 (14%) |
| Bilateral BC/two primary BCs | 9/83 (11%) | 2/10 (20%) | 2/9 (22%) |
| Additional neoplasms besides BC | 4/83 (5%) | 0/10 | 0/4 |
| Sarcoma in family or self | 10/83 (12%) | 0/10 | 0/10 |
| Brain tumor in family or self | 16/83 (20%) | 2/10 (20%) | 2/16 (13%) |
