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Table 2 Overview of all immune cell analyses between high (HMD) and low (LMD) density breast samples

From: High mammographic density in women is associated with protumor inflammation

 

Epithelium

Difference (p value)

Stroma

Difference (p value)

Marker

HMD

LMD

 

HMD

LMD

 

CD68

5.61 (0.61)

2.56 (0.75)

p =0.004

4.72 (0.9)

3.14 (0.98)

p=0.15

CD11c

1.53 (0.36)

0.5 (0.22)

p =0.02

5.30 (1.06)

2.16 (0.80)

p =0.03

CD56

5.30 (1.41)

2.29 (0.73)

p=0.07

1.81 (0.74)

0.92 (0.36)

p=0.31

CD20

1.93 (0.52)

0.31 (0.15)

p =0.0039

5.35 (2.03)

1.50 (0.59)

p=0.28

CD4

20.47 (2.69)

15.07 (2.55)

p=0.05

21.42 (2.63)

15.95 (2.64)

p =0.04

CD8

6.69 (1.43)

4.82 (1.75)

p=0.22

3.49 (0.83)

2.18 (0.66)

p=0.15

PD1

2.79 (0.52)

1.25 (0.35)

p =0.02

1.45 (0.46)

0.29 (0.20)

p =0.04

IL-6

24.68 (4.13)

18.34 (5.80)

p =0.03

21.07 (5.53)

11.24 (3.98)

p =0.006

IL-4

23.94 (5.19)

16.04 (3.60)

p=0.09

4.41 (1.29)

1.28 (0.59)

p =0.04

IFNγ

4.66 (0.88)

2.22 (0.80)

p=0.06

1.41 (0.69)

0.67 (0.36)

p=0.56

  1. Data are presented as the Mean+/- (SEM) percentage of immune + cells (ie: CD68) as a function of total epithelial cell nuclei counted in 4 random areas within each tissue sample. Data with significant differences p<0.05 are highlighted bold. N=10-15 women