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Table 2 Overview of all immune cell analyses between high (HMD) and low (LMD) density breast samples

From: High mammographic density in women is associated with protumor inflammation

  Epithelium Difference (p value) Stroma Difference (p value)
Marker HMD LMD   HMD LMD  
CD68 5.61 (0.61) 2.56 (0.75) p =0.004 4.72 (0.9) 3.14 (0.98) p=0.15
CD11c 1.53 (0.36) 0.5 (0.22) p =0.02 5.30 (1.06) 2.16 (0.80) p =0.03
CD56 5.30 (1.41) 2.29 (0.73) p=0.07 1.81 (0.74) 0.92 (0.36) p=0.31
CD20 1.93 (0.52) 0.31 (0.15) p =0.0039 5.35 (2.03) 1.50 (0.59) p=0.28
CD4 20.47 (2.69) 15.07 (2.55) p=0.05 21.42 (2.63) 15.95 (2.64) p =0.04
CD8 6.69 (1.43) 4.82 (1.75) p=0.22 3.49 (0.83) 2.18 (0.66) p=0.15
PD1 2.79 (0.52) 1.25 (0.35) p =0.02 1.45 (0.46) 0.29 (0.20) p =0.04
IL-6 24.68 (4.13) 18.34 (5.80) p =0.03 21.07 (5.53) 11.24 (3.98) p =0.006
IL-4 23.94 (5.19) 16.04 (3.60) p=0.09 4.41 (1.29) 1.28 (0.59) p =0.04
IFNγ 4.66 (0.88) 2.22 (0.80) p=0.06 1.41 (0.69) 0.67 (0.36) p=0.56
  1. Data are presented as the Mean+/- (SEM) percentage of immune + cells (ie: CD68) as a function of total epithelial cell nuclei counted in 4 random areas within each tissue sample. Data with significant differences p<0.05 are highlighted bold. N=10-15 women