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Table 1 Gene copy numbers of PC are increased in metastatic breast cancer patients. Copy number alterations in the PC gene (chromosome 11q13.2) were analyzed in the indicated datasets. The percentage of patient tumors demonstrating increases in PC gene copy number was calculated for each dataset

From: Pyruvate carboxylase supports the pulmonary tropism of metastatic breast cancer

Dataset Deep deletion Shallow deletion Diploid Gain Amplification % samples with gain in PC
METABRIC 0 145 1575 232 98 16.09
MBC Project 0 5 75 16 7 22.30
TCGA, Nature 2012 0 64 558 121 35 20.00
Mutational profiles of metastatic breast cancer 1 31 117 49 15 30.04
  1. METABRIC Molecular Taxonomy of Breast Cancer International Consortium, MBC Project Metastatic Breast Cancer Project, TCGA The Cancer Genome Atlas