Table 1 Gene copy numbers of PC are increased in metastatic breast cancer patients. Copy number alterations in the PC gene (chromosome 11q13.2) were analyzed in the indicated datasets. The percentage of patient tumors demonstrating increases in PC gene copy number was calculated for each dataset
From: Pyruvate carboxylase supports the pulmonary tropism of metastatic breast cancer
Dataset | Deep deletion | Shallow deletion | Diploid | Gain | Amplification | % samples with gain in PC |
|---|---|---|---|---|---|---|
METABRIC | 0 | 145 | 1575 | 232 | 98 | 16.09 |
MBC Project | 0 | 5 | 75 | 16 | 7 | 22.30 |
TCGA, Nature 2012 | 0 | 64 | 558 | 121 | 35 | 20.00 |
Mutational profiles of metastatic breast cancer | 1 | 31 | 117 | 49 | 15 | 30.04 |