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Table 4 Triple-negative breast cancers with high copy number variant burden1

From: The association of genomic lesions and PD-1/PD-L1 expression in resected triple-negative breast cancers

Sample

Gene lesion

PD-1

PD-L1

Neoadjuvant

TNBC-8

MSH2F289C

2

4 NT

+

TNBC-53

MLH3−/−

3

3 NT

+

TNBC-30

CHEK2−/−

1

1 NT

–

TNBC-31

BRIP1−/−

3

2 NT

–

TNBC-24

BRCAmut

4

5 T

–

TNBC-27

FBXW7S398F

2

3 NT

+

TNBC-29

PRKDCQ75R

2

4 T

+

TNBC-17

ALKBH5P303Q

1

2 NT

–

TNBC-36

DCLRE1C656_671del16

3

4 T/NT

+

TNBC-54

TBD

2

2 T/NT

+

TNBC-51

TBD

1

0

+

TNBC-23

TBD

3

4 T/NT

–

  1. 1>50 intrachromosomal copy number variants
  2. Abbreviations: NT non-tumor cells, T tumor cells, TBD to be determined, TNBC triple-negative breast cancer
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Breast Cancer Research

ISSN: 1465-542X

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