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Fig. 4 | Breast Cancer Research

Fig. 4

From: The association of genomic lesions and PD-1/PD-L1 expression in resected triple-negative breast cancers

Fig. 4

AKT pathway-specific lesions in TNBC genomes. a Whole genome (bottom panel) and locus-specific (top panel) mapping of a PTEN homozygous deletion in TNBC-1. Red shaded area denotes ADM2-defined homozygous deletion. b IGV views (top panels) of activating PIK3CAH1087R and KRASG12V mutations in genome (bottom panel) of TNBC-34. Abbreviations: NT non-tumor cells, T/NT tumor plus non-tumor cells, TNBC triple-negative breast cancer

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Breast Cancer Research

ISSN: 1465-542X

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