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Table 2 Characteristics of patients with early (< 3 years) and late (≥ 5 years) relapse

From: Circulating microRNAs in the early prediction of disease recurrence in primary breast cancer

 

Early (< 3 years)

Late (≥ 5 years)

 

Characteristic

Number

Percentage

Number

Percentage

P

Number of patients

23

17

20

15

 

Age (years)

    

nsa

 Median

55

53

 

 Range

27–75

38–74

 

Menopausal status

    

nsa

 Premenopausal

8

34.8

7

35

 

 Postmenopausal

15

65.2

13

65

 

Tumor size (cm)

    

nsa

 T1

7

30.4

8

40

 

 T2

12

52.2

10

50

 

 T3

4

17.4

2

10

 

Histological grade

    

nsa

 I

0

 

0

  

 II

10

43.5

6

30

 

 III

12

52.2

14

70

 

 Lobular

1

4.3

   

Infiltrated lymph nodes

    

nsa

 0

7

30.4

3

15

 

 1–3

9

39.2

6

30

 

  ≥ 4

7

30.4

11

55

 

ER

    

< 0.001a

 Positive

9

39.2

19

95

 

 Negative

14

60.8

1

5

 

PR

    

0.006a

 Positive

10

43.5

17

85

 

 Negative

13

56.5

3

15

 

 Unknown

     

HER2

    

nsa

 Positive

4

17.4

4

20

 

 Negative

18

78.3

16

80

 

 Unknown

1

4.3

   

Adjuvant chemotherapy

    

nsa

 Anthracyclines-based

2

8.7

2

10

 

 Taxanes+anthracyclines

16

69.6

17

85

 

 Taxane-based

5

21.7

1

5

 

Hormone therapy

    

0.002a

 Yes

12

52.2

19

95

 

 No

11

47.8

1

5

 
  1. ER estrogen receptor, PR progesterone receptor, HER2 human epidermal growth factor receptor 2, ns not significant
  2. Pearson’s chi-squared test for comparison between patients with relapse and without relapse