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Table 2 Characteristics of patients with early (< 3 years) and late (≥ 5 years) relapse

From: Circulating microRNAs in the early prediction of disease recurrence in primary breast cancer

  Early (< 3 years) Late (≥ 5 years)  
Characteristic Number Percentage Number Percentage P
Number of patients 23 17 20 15  
Age (years)      nsa
 Median 55 53  
 Range 27–75 38–74  
Menopausal status      nsa
 Premenopausal 8 34.8 7 35  
 Postmenopausal 15 65.2 13 65  
Tumor size (cm)      nsa
 T1 7 30.4 8 40  
 T2 12 52.2 10 50  
 T3 4 17.4 2 10  
Histological grade      nsa
 I 0   0   
 II 10 43.5 6 30  
 III 12 52.2 14 70  
 Lobular 1 4.3    
Infiltrated lymph nodes      nsa
 0 7 30.4 3 15  
 1–3 9 39.2 6 30  
  ≥ 4 7 30.4 11 55  
ER      < 0.001a
 Positive 9 39.2 19 95  
 Negative 14 60.8 1 5  
PR      0.006a
 Positive 10 43.5 17 85  
 Negative 13 56.5 3 15  
 Unknown      
HER2      nsa
 Positive 4 17.4 4 20  
 Negative 18 78.3 16 80  
 Unknown 1 4.3    
Adjuvant chemotherapy      nsa
 Anthracyclines-based 2 8.7 2 10  
 Taxanes+anthracyclines 16 69.6 17 85  
 Taxane-based 5 21.7 1 5  
Hormone therapy      0.002a
 Yes 12 52.2 19 95  
 No 11 47.8 1 5  
  1. ER estrogen receptor, PR progesterone receptor, HER2 human epidermal growth factor receptor 2, ns not significant
  2. Pearson’s chi-squared test for comparison between patients with relapse and without relapse