Characteristic, N (%) | Arm A N = 22 | Arm B N = 14 | Arm C N = 14 | P value |
---|---|---|---|---|
Age at randomization | ||||
18–39 years | 2 (9) | 5 (36) | 1 (7) | |
40–49 years | 8 (36) | 0 | 5 (36) | |
50–59 years | 5 (23) | 4 (29) | 7 (50) | |
≥ 60 years | 7 (32) | 5 (36) | 1 (7) | 0.02 |
Extent of surgery | ||||
Breast sparing | 9 (41) | 6 (43) | 6 (43) | |
Mastectomy | 13 (59) | 8 (57) | 8 (57) | 0.99 |
Tumor size | ||||
≤ 2.0 cm | 9 (41) | 6 (43) | 9 (64) | |
2.1–4.9 cm | 13 (59) | 7 (50) | 5 (36) | |
≥ 5.0 cm | 0 | 1 (7%) | 0 | 0.33 |
Axillary lymph node dissection | ||||
Yes | 20 (91) | 14 (100) | 14 (100) | |
No | 2 (9) | 0 | 0 | 0.27 |
Sentinel node biopsy | ||||
Yes | 8 (36) | 8 (57) | 6 (43) | |
No | 14 (64) | 6 (43) | 8 (57) | 0.47 |
Tumor grade | ||||
Low/Intermediate | 4 (18) | 4 (29) | 6 (43) | |
High | 18 (82) | 10 (71) | 8 (57) | 0.28 |
T stage | ||||
1 | 9 (41) | 6 (43) | 9 (64) | |
2 | 13 (59) | 7 (50) | 5 (36) | |
3 | 0 | 1 (7) | 0 | 0.33 |
N stage | ||||
1 | 21 (95) | 13 (93) | 14 (100) | |
2 | 1 (5) | 1 (7) | 0 | 0.62 |