Skip to main content

Table 3 Mean amide proton transfer (APT) signal in the tumor before and after the first cycle of neoadjuvant chemotherapy (NAC)

From: Amide chemical exchange saturation transfer at 7 T: a possible biomarker for detecting early response to neoadjuvant chemotherapy in breast cancer patients

Patient

Pathological response

Mean (± SD) APT signal before NAC

Mean (± SD) APT signal after the first cycle of NAC

Delta mean APT signal

P valuea

1

5

0.0494 (± 0.0062)

0.0388 (± 0.0046)

− 0.0106

< 0.0001*

2

3

0.0319 (± 0.0046)

0.0311 (± 0.0056)

−0.0008

0.0458*

3R

4

0.0289 (± 0.0055)

0.0231 (± 0.0046)

−0.0058

0.0004*

3L

4

0.0189 (± 0.0020)

0.0149 (± 0.0034)

−0.0040

0.0003*

4

5

0.0420 (± 0.0098)

0.0275 (± 0.0043)

−0.0145

< 0.0001*

5

2

0.0132 (± 0.0037)

0.0140 (± 0.0040)

+0.0008

0.5749

6

4

0.0272 (± 0.0049)

0.0229 (± 0.0053)

−0.0043

0.4135

7

5

0.0254 (± 0.0056)

0.0252 (± 0.0043)

−0.0002

0.5259

8

3

0.0319 (± 0.0068)

0.0326 (± 0.0054)

+0.0007

0.4170

9

2

0.0381 (± 0.0045)

0.0465 (± 0.0072)

+0.0084

0.0001*

  1. aUnpaired Mann-Whitney test with two-tailed distribution
  2. *Significant difference