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Fig. 1 | Breast Cancer Research

Fig. 1

From: NDRG1 regulates neutral lipid metabolism in breast cancer cells

Fig. 1

NDRG1 expression is associated with adverse outcomes and altered metabolism in breast cancer. a Meta-analysis of 23 distinct breast cancer cohorts (n = 3554 subjects). Kaplan-Meier curve of recurrence-free survival analysis of NDRG1 mRNA expression (upper quartile (Q) versus lower three quartiles). Post-DX, Post-diagnosis. b Metastasis-free survival of NDRG1 quartiles in the Van’t Veer cohort (n = 295). c NDRG1 expression in estrogen receptor (ER)+/− groups of the the Van’t Veer cohort. d The distribution of total Van’t Veer cohort NDRG1 expression quartiles in ER+ and ER- tumors. The unequal distribution further reflects the data in (c). e, f Metastasis-free survival using the 42-gene signature in The Cancer Genome Atlas breast cancer cohort (n = 962), and the Van’t Veer breast cancer cohort (n = 295)

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