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Fig. 3 | Breast Cancer Research

Fig. 3

From: Longitudinal enumeration and cluster evaluation of circulating tumor cells improve prognostication for patients with newly diagnosed metastatic breast cancer in a prospective observational trial

Fig. 3

Progression-free survival (PFS) and overall survival (OS) by circulating tumor cell (CTC) count and CTC cluster detection. Kaplan-Meier curves displaying PFS and OS by four groups including CTC count and CTC cluster detection at baseline (a-b) at 1 month (c-d), 3 months (e-f) and 6 months (g-h). The four groups were patients with no CTCs, patients with 1–4 CTCs and no clusters, patients with ≥ 5 CTCs and no clusters, and patients with > 1 CTC and clusters. Analyses at 1, 3, and 6 months were performed with landmark analysis where the follow-up time was recalculated with a new starting date from the 1, 3, and 6-month samples, respectively

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