Table 1 Characteristics of breast cancer cases and controls, matched on age and menopausal status
Characteristic | Breast cancer cases (n = 62) | Controls (n = 177) | P |
|---|---|---|---|
Age at MBI (years)a | 60.3 ± 10.6 (38–88) | 60.2 ± 10.4 (38–86) | NA |
Menopausal status | NA | ||
Premenopausal | 13 (21) | 38 (22) | |
Postmenopausal | 49 (79) | 138 (78) | |
Body mass index (kg/m2)a | 27.7 ± 6.4 (18.8–55.5) | 26.2 ± 4.7 (18.6–44.3) | 0.06 |
Postmenopausal systemic hormone therapyb | 0.57 | ||
Current use at MBI | 13 (27) | 44 (31) | |
No current use at MBI | 36 (73) | 97 (69) | |
BI-RADS density | 0.81 | ||
Almost entirely fat | 1 (2) | 3 (2) | |
Scattered fibroglandular densities | 10 (16) | 34 (19) | |
Heterogeneously dense | 44 (71) | 113 (64) | |
Extremely dense | 7 (11) | 26 (15) | |
Percent densitya | 24.8 ± 8.3 (3.5–48.0) | 24.6 ± 10.2 (1.8–53.8) | 0.93 |
Tumor invasiveness | |||
Invasive | 45 (73) | NA | |
DCIS | 17 (27) | NA | |
Gail model 5-year riska | 2.7 ± 1.5 (0.6–7.2) | 2.4 ± 1.5 (0.5–9.5) | 0.23 |
BCSC model 5-year riska | 2.6 ± 1.2 (0.7–5.4) | 2.3 ± 1.5 (0.4–13.2) | 0.29 |
Family history of breast cancer | 0.45 | ||
One or more first-degree relatives | 33 (53) | 86 (48) | |
No first-degree relatives | 29 (47) | 93 (52) | |
Personal history of biopsy showing atypia or LCIS | 0.07 | ||
Yes | 6 (10) | 6 (3) | |
No | 56 (90) | 173 (97) | |