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Fig. 5 | Breast Cancer Research

Fig. 5

From: Hyperprolactinemia-inducing antipsychotics increase breast cancer risk by activating JAK-STAT5 in precancerous lesions

Fig. 5

Ruxolitinib (Ruxo) treatment restore the apoptosis anticancer barrier and blocks early lesion expansion. a Immunofluorescence staining for Ki67 and the resulting dot plot. b and c Immunofluorescence staining for cleaved caspase 3 (b) and TUNEL assay (c) with the accompanying dot plots. d Immunohistochemistry analysis and the accompanying dot plot for the HA tag on RCAS-caErbB2 provirus. The p values were determined by the Mann-Whitney test. Each dot in these plots represents one mouse. Risp, risperidone

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