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Fig. 3 | Breast Cancer Research

Fig. 3

From: Hyperprolactinemia-inducing antipsychotics increase breast cancer risk by activating JAK-STAT5 in precancerous lesions

Fig. 3

Risperidone treatment increases signal transducer and activator of transcription 5 (STAT5) activity. a Immunohistochemistry staining for pSTAT5 in early precancerous lesions and in normal ducts (inset) and the accompany dot plot. b Immunohistochemistry analysis of the downstream effector of STAT5, β-casein, in early lesions and normal ducts (inset). c Serum prolactin (PRL) levels. d Immunofluorescence and the accompanying dot plot for Bcl-xL. The p values were determined by the Mann-Whitney test. Each dot in these plots represents one mouse

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