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Table 5 Summary of neuropsychological testing data with NIH Toolbox for Cognition (score and SD)

From: Assessing brain volume changes in older women with breast cancer receiving adjuvant chemotherapy: a brain magnetic resonance imaging pilot study

NIH Toolbox score

Time point 1

Time point 2

Change over time

Chemotherapy group

Healthy controls

Chemotherapy group

Healthy controls

Chemotherapy group

Healthy controls

p**

Crystallized composite

110.87 (16.12)

107.38 (15.57)

110.56 (11.82)

107.05 (18.53)

− 0.31 (7.21)

− 0.33 (6.44)

1.00

Fluid composite

99.69 (14.43)

99.22 (10.65)

100.23 (14.62)

105.08 (15.85)

0.54 (11.66)

5.86 (11.84)

0.23

Total composite

105.10 (19.11)

101.48 (15.02)

104.14 (15.05)

105.11 (20.37)

− 0.95 (10.00)

3.63 (8.78)

0.20

Dimensional change card sort

100.66 (11.83)

101.78 (12.62)

101.70 (7.06)

106.91 (9.64)

1.04 (8.37)

5.13 (12.26)

0.29

Flanker Inhibitory control

95.78 (10.97)

96.92 (9.12)

92.50 (9.25)

99.74 (6.11)

− 3.27 (12.33)

2.81 (6.77)

0.11

Working memory

101.45 (16.31)

100.18 (16.35)

107.01 (10.64)

105.00 (17.00)

5.57 (10.19)

4.83 (14.10)

0.87

Oral reading recognition

111.52 (11.95)

103.37 (12.51)

107.80 (12.33)

103.45 (14.00)

−3.71 (5.74)*

0.09 (6.91)

0.11

Processing speed

91.29 (14.08)

96.84 (14.06)

91.14 (17.05)

95.39 (16.45)

− 0.14 (14.94)

− 1.44 (14.94)

0.81

Episodic memory

111.73 (20.06)

103.49 (15.26)

109.70 (21.33)

110.29 (25.05)

−2.02 (12.24)

6.80 (21.18)

0.17

Picture vocabulary

107.06 (14.94)

109.13 (16.63)

110.30 (8.88)

107.66 (16.52)

3.23 (9.94)

− 1.47 (6.30)

0.14

  1. *p = 0.02
  2. **p comparing change over time between chemotherapy group and healthy control group. Bold numbers indicate key findings