Skip to main content

Table 3 Multivariable analysis of patient demographics and characteristics comparing overall survival

From: Practice patterns and outcomes for patients with node-negative hormone receptor-positive breast cancer and intermediate 21-gene Recurrence Scores

  Adjusted hazard ratio 95% confidence interval p value
Facility type
 Community cancer program 2.44 1.26–4.75 0.01
 Comprehensive community cancer program 1.54 0.92–2.58 0.10
 Academic/research program REF   
 Other 1.45 0.66–3.17 0.36
Age category (years)
 < 40 REF   
 40–49 1.41 0.16–12.31 0.76
 50–59 2.36 0.29–19.42 0.43
 60–69 2.56 0.31–21.28 0.38
 70–79 5.02 0.58–43.63 0.14
 80+ 8.40 0.89–89.81 0.08
Race/ethnicity
 Non-Hispanic White REF   
 Non-Hispanic Black 1.99 1.12–3.52 0.02
 Hispanic 0.51 0.12–2.11 0.36
 Non-Hispanic Asian/Pacific 0.86 0.21–3.56 0.84
 Other 0.46 0.14–1.44 0.18
Primary payer
 Not insured 1.78 0.43–7.41 0.43
 Private insurance REF   
 Medicaid 2.21 1.01–4.80 0.05
 Medicare 1.38 0.77–2.48 0.28
 Other 2.76 0.97–7.87 0.06
Urban/rural
 Metro counties REF   
 Urban counties 1.04 0.60–1.82 0.89
 Rural counties 1.78 0.55–5.76 0.33
 Unknown 0.76 0.18–3.14 0.70
Charlson–Deyo score
 0 REF   
 1 3.00 1.92–4.67 < 0.001
 2 6.74 3.40–13.34 < 0.001
Grade
 Well differentiated, differentiated, NOS REF   
 Moderately differentiated, moderately well differentiated, intermediate differentiation 1.13 0.69–1.87 0.63
 Poorly differentiated 2.00 1.10–3.63 0.02
AJCC pathologic stage
 T1C REF   
 T2 2.17 1.45–3.25 < 0.001
Lymphovascular invasion
 Not present REF   
 Present 1.23 0.70–2.16 0.48
Type of surgery
 Breast conservation REF   
 Mastectomy 0.45 0.20–1.02 0.06
Radiation therapy
 None REF   
 Beam radiation 0.38 0.17–0.83 0.01
  1. AJCC American Joint Committee on Cancer, NOS not otherwise specified, REF reference
\