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Table 3 Correlation coefficients (r) for expression levels of four proteins in patients with breast IDC (n = 218)

From: Isocitrate dehydrogenase 1–snail axis dysfunction significantly correlates with breast cancer prognosis and regulates cell invasion ability

Variables IDH1 HIF1α Snail Twist
IDH1 - - - -
- - - -
HIF1α r = 0.221 - -  
p = 0.001 - -
Snail r = −0.141 r = 0.194 -  
p = 0.037 p = 0.004 -
Twist r = 0.172 r = 0.424 r = 0.115 -
p = 0.011 p <0.001 p = 0.090 -
  1. The correlation coefficients and p values were estimated by Spearman’s rank correlation
  2. IDC invasive ductal carcinoma, IDH1 isocitrate dehydrogenase 1, HIF1α hypoxia-inducible factor-1 alpha
  3. Bold italic values denote statistically significant
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