Characteristic | Number (percentage) | DSS | DFS |
---|
CHRa (95% CI) | p value | AHRb (95% CI) | p value | CHRa (95% CI) | p value | AHRb (95% CI) | p value |
---|
IDH1 status | (n = 249) | | | | | | | | |
High (5–7) | 164 (65.9) | 1.00 | | 1.00 | | 1.00 | | 1.00 | |
Low (0–4) | 85 (34.1) | 1.64 (1.14–2.38) |
0.008
| 1.57 (1.08–2.30) |
0.020
| 1.58 (1.07–2.34) |
0.023
| 1.40 (0.93–2.10) | 0.106 |
- Abbreviations: IDH isocitrate dehydrogenase, IDC invasive ductal carcinoma, DSS disease-specific survival, DFS disease-free survival, CHR crude hazard ratio, AHR adjusted hazard ratio
- aCHRs were estimated by univariate Cox regression
- bAHRs were adjusted for American Joint Committee on Cancer pathological stage (II and III vs. I), grading (III vs. I and II), incomplete or inappropriate adjuvant treatment vs. non-treatment or complete adjuvant treatment, and molecular subtypes (luminal B, human epidermal growth factor receptor 2 overexpression and basal-like vs. luminal A) in multivariate Cox regression
- Bold italic values denote statistically significant