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Fig. 3 | Breast Cancer Research

Fig. 3

From: Morphology and genomic hallmarks of breast tumours developed by ATM deleterious variant carriers

Fig. 3

Copy number variation and single-nucleotide variant (SNV) profiles of ataxia-telangiectasia mutated (ATM)-associated tumours obtained by deep whole-genome sequencing (WGS). a Cumulative profiles of copy number gains, losses and of loss of heterozygosity (LOH) regions obtained from WGS of four ATM-associated tumours. Black boxes indicate the genomic regions identified in the OncoScan analysis; green boxes indicate the new genomic regions identified by WGS. b Venn diagram representing the number of somatic SNVs and indels shared between the four tumours. c Venn diagram representing the number of genes altered and shared between the four tumours

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