Table 3 MRI-based response patterns of breast carcinomas on breast MRI halfway through NAC and pathological response per MRI-based response pattern
Reader 1 | Reader 2 | |||||||
|---|---|---|---|---|---|---|---|---|
Number (percentage) | Tumor response > 50% | Diameter reduction > 50% | pCR | Number (percentage) | Tumor response > 50% | Diameter reduction > 50% | pCR | |
Complete radiologic response (type 0) | 5 (7%) | 4/5 (80%) | 4/5 (80%) | 4/5 (80%) | 7 (9%) | 7/7 (100%) | 6/7 (86%) | 6/7 (86%) |
Concentric shrinkage (type 1) | 38 (51%) | 30/38 (79%) | 14/38 (37%) | 9/38 (24%) | 22 (29%) | 17/22 (77%) | 8/22 (36%) | 6/22 (27%) |
Crumbling (type 2) | 21 (28%) | 13/21 (62%) | 8/19a (42%) | 3/21 (14%) | 24 (32%) | 16/24 (67%) | 9/24 (38%) | 3/24 (13%) |
Diffuse enhancement (type 3) | 0 (0%) | n.a. | n.a. | n.a. | 3 (4%) | 3/3 (100%) | 0/2a (0%) | 0/3 (0%) |
Stable disease (type 4) | 11 (15%) | 5/11 (55%) | 4/11 (36%) | 0/11 (0%) | 18 (27%) | 9/18 (50%) | 7/17a (41%) | 1/18 (6%) |
Progressive disease (type 5) | 0 (0%) | n.a. | n.a. | n.a. | 1 (1%) | 0/1 (0%) | 0/1 (0%) | 0/1 (0%) |
Total | 75 (100%) | 52/75 (69%) | 30/73a (41%) | 16/75 (21%) | 75 (100%) | 52/75 (69%) | 30/73a (41%) | 16/75 (21%) |