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Table 3 MRI-based response patterns of breast carcinomas on breast MRI halfway through NAC and pathological response per MRI-based response pattern

From: MRI-based response patterns during neoadjuvant chemotherapy can predict pathological (complete) response in patients with breast cancer

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Number (percentage) Tumor response > 50% Diameter reduction > 50% pCR Number (percentage) Tumor response > 50% Diameter reduction > 50% pCR
Complete radiologic response (type 0) 5 (7%) 4/5 (80%) 4/5 (80%) 4/5 (80%) 7 (9%) 7/7 (100%) 6/7 (86%) 6/7 (86%)
Concentric shrinkage (type 1) 38 (51%) 30/38 (79%) 14/38 (37%) 9/38 (24%) 22 (29%) 17/22 (77%) 8/22 (36%) 6/22 (27%)
Crumbling (type 2) 21 (28%) 13/21 (62%) 8/19a (42%) 3/21 (14%) 24 (32%) 16/24 (67%) 9/24 (38%) 3/24 (13%)
Diffuse enhancement (type 3) 0 (0%) n.a. n.a. n.a. 3 (4%) 3/3 (100%) 0/2a (0%) 0/3 (0%)
Stable disease (type 4) 11 (15%) 5/11 (55%) 4/11 (36%) 0/11 (0%) 18 (27%) 9/18 (50%) 7/17a (41%) 1/18 (6%)
Progressive disease (type 5) 0 (0%) n.a. n.a. n.a. 1 (1%) 0/1 (0%) 0/1 (0%) 0/1 (0%)
Total 75 (100%) 52/75 (69%) 30/73a (41%) 16/75 (21%) 75 (100%) 52/75 (69%) 30/73a (41%) 16/75 (21%)
  1. Abbreviations: MRI magnetic resonance imaging, pCR pathological complete response, n.a. not applicable
  2. aIn two tumors no diameter assessment was possible on baseline MRI
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