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Table 1 Characteristics of women with contralateral breast cancer (CBC) (cases) and unilateral breast cancer (UBC) controls

From: The association of mammographic density with risk of contralateral breast cancer and change in density with treatment in the WECARE study

 

CBC (n = 362)

UBC (n = 403)

 

Mean (SD)

Mean (SD)

Age at mammogram before/at 1st diagnosis (years)

46 (6)

46 (6)

Age at mammogram after 1st diagnosis (years)

47 (6)

47 (6)

Follow-up timea (years)

7.9 (3.8)

8.0 (4.0)

BMI at 1st diagnosis (kg/m2)

25.2 (5.5)

25.2 (5.7)

BMIb at mammogram after 1st diagnosis (kg/m2)

25.2 (5.4)

25.8 (5.7)

Percent mammographic density before/at 1st diagnosis

37.6 (18.1)

35.8 (18.3)

Percent mammographic density after 1st diagnosis

31.4 (18.3)

28.0 (16.7)

 

N (%)

N (%)

Study center

  

 Northern California

179 (49)

213 (53)

 Seattle

82 (23)

80 (20)

 Ontario

52 (14)

64 (16)

 Iowa

49 (14)

46 (11)

Race

  

 Non-Hispanic white

295 (83)

334 (81)

 Other

67 (17)

69 (19)

Histologic type at 1st diagnosis

  

 Non-lobular

321 (89)

353 (88)

 Lobular

41 (11)

50 (12)

Stage at 1st diagnosis

  

 Local

251 (69)

254 (63)

 Regional

106 (29)

143 (35)

 Missing

5 (1)

6 (1)

Estrogen receptor at 1st diagnosis

  

 Positive

213 (59)

273 (68)

 Negative

129 (36)

105 (26)

 Missing

20 (6)

25 (6)

Chemotherapy at 1st diagnosis

  

 Yes

236 (65)

272 (67)

 No

126 (35)

131 (33)

Radiation at 1st diagnosis

  

 Yes

251 (69)

179 (69)

 No

111 (31)

124 (31)

Tamoxifen at 1st diagnosis

  

 Yes

158 (44)

221 (55)

 No

204 (56)

182 (45)

Family historyc of breast cancer

  

 Yes

123 (34)

89 (22)

 No

234 (65)

306 (76)

 Adopted/missing

5 (1)

8 (2)

Age at menarche (years)

  

  <13

194 (54)

193 (48)

  ≥13

167 (46)

209 (52)

 Missing

1 (< 1)

1 (< 1)

Full-term pregnancies

  

 None

101 (28)

95 (24)

 1–3

241 (67)

278 (69)

  ≥4

20 (6)

30 (7)

  1. SD standard deviation, BMI body mass index
  2. aTime interval between first diagnosis and reference date defined as time of second diagnosis in CBC cases and time of second diagnosis in matched case for UBC controls
  3. bBMI estimated from reported BMI at first diagnosis and reported BMI at reference date using interpolation
  4. cFirst-degree family history