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Table 3 Characteristics of the included studies for estimating the diagnostic accuracy of the Gail model

From: Assessment of performance of the Gail model for predicting breast cancer risk: a systematic review and meta-analysis with trial sequential analysis

Ref Author Publication year Geographic background Study design Gail model version Sample size Mean age (years) Study population Time period TP FP FN TN
[11] Rockhill 2001 America Cohort 2 82,109 45–71 Nurses’ Health Study (NHS) 1992–1997 596 27,457 758 53,298
[25] Weik 2005 America Cross-sectional 2 543 20–80 Women who underwent a stereotactic or ultrasound-guided breast biopsy examination 2001–2003 58 95 81 309
[26] Adams-Campbell-1 2007 America Nested case–control 1 1450 21–69 Black Women’s Health Study (BWHS) 1995–2003 130 102 595 623
[26] Adams-Campbell-2 2007 America Nested case–control 3 1450 21–69 Black Women’s Health Study (BWHS) 1995–2003 30 19 695 706
[31] Chlebowski 2007 America Cohort 2 64,568 63 Predicted ER-positive breast cancer in Women’s Health Initiative (WHI) study 1993–2005 462 22,276 461 41,369
[15] Tice 2008 America Cohort 2 629,229 40–74 National Cancer Institute-funded Breast Cancer Surveillance Consortium (BCSC) Since1994 2442 103,852 6342 516,593
[47] Li 2009 China Case–control 2 420 40–75 Bao’an Maternal and Child Health Care Hospital, Shenzhen 2003–2008 98 20 5 297
[44] Wang 2010 China Case–control 1 228 56 Breast cancer and controls in Shenzhou Hospital of Shenyang Medical College 1998–2007 65 10 4 149
[37] Ulusoy 2010 Turkey Case–control 2 1290 49.49 Breast cancer and controls in Ankara University School of Medicine 2002–2008 87 51 563 589
[33] Buron 2013 Spain Cohort 2 2200 49–64 Participants with a positive screening mammogram in “Parc de Salut Mar” breast cancer screening program 1996–2010 24 449 28 1161
[48] Zhou 2014 China Case–control 1 280 48.62 Breast cancer and controls in Huangpu District in Shanghai of China 2010 72 11 71 126
[45] Duan 2014 China Case–control 2 400 52.58 Breast cancer and controls in the First Affiliated Hospital of KunMing Medical University 2007–2011 24 7 176 193
[49] Huang 2015 China Case–control 1 317 54.1 Breast cancer and controls in Guangxi Maternal and Child Health Care Hospital 2012–2014 116 13 41 147
[50] An 2016 China Case–control 2 567 > 40 Breast cancer and controls in China Japan Union Hospital of Jilin University 2011–2015 207 105 93 162
  1. Note: Gail model type 1, original Gail model; Gail model type 2, modified Gail model for Caucasian-American; Gail model type 3, modified Gail model for African-American
  2. TP true positive, FP false positive, FN false negative, TN true negative, ER estrogen receptor