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Table 7 SLC7A5 protein expression and patient outcome in the combined discovery and validation sets in all cases and in ER-positive high proliferation tumours

From: The amino acid transporter SLC7A5 confers a poor prognosis in the highly proliferative breast cancer subtypes and is a key therapeutic target in luminal B tumours

SLC7A5 protein

 

All cases

ER+ high proliferation

Parameter

Hazard ratio (95% CI)

p value

Adjusted p value

Hazard ratio (95% CI)

p value

Adjusted p value

SLC7A5

1.001 (1.000–1.003)

0.063

0.126

1.004 (1.001–1.006)

0.006

0.024

Lymph node stage

2.060 (1.813–2.341)

1.7 × 10−28

<0.0001

1.756 (1.427–2.161)

1.04 × 10−7

<0.0001

Size

1.365 (1.111–1.678)

0.003

0.009

1.169 (0.838–1.632)

0.358

0.716

Grade

2.454 (2.023–2.977)

1.8 × 10−20

<0.0001

1.756 (1.154–2.672)

0.009

0.027

  1. p value in bold in these tables means statistically significant associations