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Table 1 Sample demographics

From: Affinity proteomic profiling of plasma for proteins associated to area-based mammographic breast density

  Sample set 1 Sample set 2
Characteristics All samples
N = 729
Low mammographic density
N = 295
High mammographic density
N = 295
Karma normal
N = 139
All samples
N = 600
Low mammographic density
N = 300
High mammographic density
N = 300
Mean (SD)
 Age, years 53.6 (9.5) 52.9 (9.5) 52.9 (9.5) 56.5 (9.1) 54.2 (9.6) 54.2 (9.6) 54.2 (9.6)
 BMI, kg/m2 24.4 (3.1) 24.4 (2.6) 24.2 (2.6) 25.2 (4.5) 24.1 (2.7) 24.2 (2.7) 24.1 (2.7)
 Absolute breast dense area, cm2 35.4 (29.3) 17.0 (13.9) 56.6 (30.0) 29.4 (22.1) 37.3 (31.2) 15.7 (12.5) 58.9 (29.4)
 Absolute volumetric breast density, cm3 72.0 (43.6) 33.9 (10.0) 108.5 (36.2) 75.3 (32.4) 73.0 (49.5) 33.4 (10.8) 112.5 (40.7)
 Age at menarche, years 13.1 (1.5) 13.0 (1.5) 13.2 (1.5) 13.1 (1.4) 13.1 (1.4) 13.1 (1.4) 13.1 (1.3)
 Age at first birth, years 27.5 (5.4) 27.5 (5.3) 28.2 (5.7) 26.2 (4.8) 27.8 (5.2) 27.4 (5.1) 28.3 (5.3)
 Age at menopause, years 50.2 (5.5) 50.3 (5.8) 50.0 (5.1) 50.3 (5.6) 49.6 (5.3) 49.2 (5.4) 50.1 (5.2)
Number (percent)
 Nulliparous 86 (11.9) 18 (6.1) 51 (17.3) 17 (12.7) 103 (17.2) 37 (12.3) 66 (22.0)
 Menopausal status
  Premenopausal 337 (46.4) 140 (47.5) 157 (53.2) 40 (29.4) 268 (44.7) 129 (43.0) 139 (46.3)
  Postmenopausal 389 (53.6) 155 (52.5) 138 (46.8) 96 (70.6) 332 (55.3) 171 (57.0) 161 (53.7)
 HRT use ever
  No 527 (79.0) 233 (79.0) 243 (82.4) 96 (71.6) 488 (81.3) 241 (80.3) 247 (82.39
  Yes 152 (21.0) 62 (21.0) 52 (17.6) 38 (28.4) 112 (18.7) 59 (19.7) 53 (17.7)
  1. Number of individuals with missing data for the following variables: body mass index (BMI) (N = 1), mammographic density (N = 1), age at menarche (N = 31), age at first birth (N = 198), age at menopause (N = 420), parity (N = 5), postmenopausal status (N = 3), and hormone replacement therapy (HRT) use ever (N = 5)
  2. SD standard deviation
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