TY - JOUR AU - Busby, John AU - Mills, Ken AU - Zhang, Shu-Dong AU - Liberante, Fabio Giuseppe AU - Cardwell, Chris R. PY - 2018 DA - 2018/01/19 TI - Selective serotonin reuptake inhibitor use and breast cancer survival: a population-based cohort study JO - Breast Cancer Research SP - 4 VL - 20 IS - 1 AB - Nearly 50% of breast cancer patients suffer from depression or anxiety. Selective serotonin reuptake inhibitors (SSRIs), the first-line pharmacological treatment for depression, have been implicated in breast cancer development through increased prolactin levels and tamoxifen metabolism inhibition. Previous studies of breast cancer progression have focused on tamoxifen users, or have been limited by their small sample size and methodology. Therefore, we used UK population-based data to more robustly investigate the association between SSRI use and cancer-specific mortality. SN - 1465-542X UR - https://doi.org/10.1186/s13058-017-0928-0 DO - 10.1186/s13058-017-0928-0 ID - Busby2018 ER -