Identifying biomarkers of breast cancer micrometastatic disease in bone marrow using a patient-derived xenograft mouse model

Table 4 WHIM bone marrow (BM) gene transcripts with expression that is statistically greater than background expression in normal human BM (p < 0.05, corrected for multiple comparisons using the false discovery (FDR) method)

Gene	Gene name	Drugs available against target gene
CD163	CD163 molecule
PDGFC	Platelet derived growth factor C
GLIPR1	GLI pathogenesis related 1
ANXA5	Annexin A5
CPVL	Carboxypeptidase, vitellogenic like
PF4	Platelet factor 4
CYP1B1	Cytochrome P450 family 1 subfamily B member 1	Yes [43]
EPB41L3	Erythrocyte membrane protein band 4.1 like 3
MEIS1	Meis homeobox 1
TNFRSF17	TNF receptor superfamily member 17
DLC1	DLC1 rho GTPase activating protein
HEBP1	Heme binding protein 1
CFDP1	Craniofacial development protein 1
CD36	CD36 molecule
CD33	CD33 molecule	Gemtuzumab ozogamicin, acute myeloid leukemia [44,45,46]
UGDH	UDP-glucose 6-dehydrogenase
CD44	CD44 molecule

ISSN: 1465-542X