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Table 1 Patient demographics and characteristics

From: Serum concentrations of active tamoxifen metabolites predict long-term survival in adjuvantly treated breast cancer patients

Characteristics

Present study

population

(n = 99)

Relapse free

at 3 years

(n = 356)

Differences between

the groups

(P values)

Age at diagnosis (years)

   

 Mean (median)

58 (56)

57 (56)

 

 Range

34–78

28–85

0.380

Menopause status, n (%)

   

 Pre (< 55 years)

40 (40%)

151 (42%)

 

 Post (≥ 55 years)

59 (60%)

205 (58%)

0.710

Histology, n (%)

   

 IDC

74 (75%)

251 (76%)

0.109

 ILC

24 (24%)

69 (19%)

 Other infiltrating cancer

1 (1%)

16 (5%)

Tumor size, n (%)

   

 pT1

50 (51%)

253 (71%)

< 0.001*

 pT2

49 (49%)

87 (25%)

 pT3

12 (3%)

 

 pT4

0 (0%)

 

 pTx

3 (1%)

 

Tumor grade, n (%)

   

 G1

18 (18%)

110 (31%)

0.009

 G2

67 (68%)

184 (52%)

 G3

12 (12%)

56 (15%)

 Not reported

2 (2%)

6 (2%)

Node status, n (%)

   

 Positive

57 (58%)

93 (71%)

< 0.001

 Negative

41 (41%)

257 (27%)

 Not reported

1 (1%)

6 (2%)

HER2/neu status, n (%)

   

 HER2+

7 (7%)

36 (10%)

0.193

 HER2

89 (90%)

298 (84%)

 Unknown

3 (3%)

22 (6%)

  1. Comparison of the demographic and clinical characteristics between the patients in the present study population and 356 relapse-free patients from the original population [17]
  2. The present study population comprises more patients with pT2 tumors, higher grade, and node-positive status due to treatment selection
  3. *The present study population only included operable breast cancer patients; therefore p value of tumor size comparison is between pT1 and pT2 populations
  4. IDC invasive ductal carcinoma, ILC invasive lobular carcinoma, pT pathological tumor size