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Table 5 Modelling results for screen-detected and interval cancer

From: A novel and fully automated mammographic texture analysis for risk prediction: results from two case-control studies

 

Risk score

Contrast

Sum average 16

Sum average 32

Sum average 64

Volumetric PD

Standardized OR for screen-detected cancer

1.15

0.88

1.09

1.11

1.20

1.13

(0.99–1.35)

(0.75–1.04)

(0.93–1.26)

(0.95–1.30)

(1.02–1.40)

(0.94–1.35)

Standardized OR for interval cancer

2.09

0.84

2.12

2.15

1.91

1.53

(1.59–2.74)

(0.66–1.06)

(1.59–2.81)

(1.62–2.86)

(1.48–2.47)

(1.21–1.92)

Δχ2

15.27

0.15

18.53

17.84

9.80

4.38

P value

0.0001

0.70

<0.0001

<0.0001

0.002

0.036

  1. Standardized odds ratio (OR) is the change in odds for a standard deviation (in controls) increase in image features; the 95% confidence intervals are in brackets. Sum average 16, 32 and 64 are the texture feature sum average using images downsized by a factor of 16, 32 and 64
  2. The Δχ 2 and p values refer to likelihood-ratio tests on whether there is a significant difference between screen-detected and interval cancers (i.e. significance of interaction terms)
  3. PD percent density
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Breast Cancer Research

ISSN: 1465-542X

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