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Fig. 3 | Breast Cancer Research

Fig. 3

From: Proteomic profiling of breast cancer metabolism identifies SHMT2 and ASCT2 as prognostic factors

Fig. 3

Kaplan-Meier survival estimates and boxplot representation of key targets associated with survival. Kaplan-Meier plots of serine hydroxymethyltransferase 2 (SHMT2) and ASC amino-acid transporter 2 (ASCT2) for overall survival (OS) (a), and recurrence-free survival (RFS) (b). Statistical difference in outcome between high (n = 400) and low (n = 401) expression were compared by log-rank test. Boxplots represent the relative target protein expression per receptor-defined subtype, luminal A-like (n = 510), luminal B-like human epidermal growth factor receptor 2-negative (HER2-neg) (n = 104), luminal B-like HER2-positive (HER2-pos) (n = 74), HER2-pos (n = 36), triple negative breast cancer (TNBC) (n = 77). FDR, false discovery rate; pval, p value

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