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Fig. 1 | Breast Cancer Research

Fig. 1

From: Proteomic profiling of breast cancer metabolism identifies SHMT2 and ASCT2 as prognostic factors

Fig. 1

Unsupervised clustering of protein profiles. The heatmap represents expression levels of 37 metabolism related proteins after unsupervised hierarchical clustering. The dataset consists of 801 tumor specimen. The z scores of log2 transformed protein expression levels are color-coded on a low-to-high scale (green-black-magenta). Dendrogram branches divide the patient set into a green and violet cluster and protein targets into a “diffuse” and “compact” cluster. Annotation bars include receptor-defined subtypes (a), histological grade (b), histology (c), menopausal status (d), nodal status (e) and T stage (f). HER2, human epidermal growth factor receptor 2; TNBC, triple negative breast cancer

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