Table 4 Enriched gene sets^a by recent alcohol consumption^b in ER- tumors in the NHS and the NHSII

 REACTOME_TRANSLATION

144

2.31

0.0002

 REACTOME_CYTOKINE_SIGNALING_IN_IMMUNE_SYSTEM

218

2.32

0.0003

 KEGG_UBIQUITIN_MEDIATED_PROTEOLYSIS

124

2.38

0.001

 REACTOME_METABOLISM_OF_MRNA

206

2.25

0.001

 PROTEIN_RNA_COMPLEX_ASSEMBLY

60

2.25

0.001

 REACTOME_INTERFERON_SIGNALING

129

2.21

0.001

 REACTOME_METABOLISM_OF_RNA

248

2.18

0.001

 REACTOME_SRP_DEPENDENT_COTRANSLATIONAL_PROTEIN_TARGETING_TO_MEMBRANE

108

2.17

0.001

 REACTOME_INFLUENZA_LIFE_CYCLE

134

2.13

0.002

 KEGG_SPLICEOSOME

122

2.10

0.002

 KEGG_RIBOSOME

84

2.08

0.003

 BIOCARTA_CDC42RAC_PATHWAY

15

2.08

0.003

 REACTOME_3_UTR_MEDIATED_TRANSLATIONAL_REGULATION

104

2.07

0.003

 REACTOME_NONSENSE_MEDIATED_DECAY_ENHANCED_BY_THE_EXON_JUNCTION_COMPLEX

106

2.05

0.003

 REACTOME_PEPTIDE_CHAIN_ELONGATION

85

2.03

0.004

 REACTOME_ANTIVIRAL_MECHANISM_BY_IFN_STIMULATED_GENES

61

2.01

0.005

 RIBONUCLEOPROTEIN_COMPLEX_BIOGENESIS_AND_ASSEMBLY

79

1.97

0.006

 REACTOME_PROCESSING_OF_CAPPED_INTRON_CONTAINING_PRE_MRNA

132

1.97

0.006

 REACTOME_INFLUENZA_VIRAL_RNA_TRANSCRIPTION_AND_REPLICATION

101

1.94

0.008

 REACTOME_MRNA_PROCESSING

151

1.92

0.009

 RNA_PROCESSING

159

1.88

0.013

 BIOCARTA_G1_PATHWAY

25

1.84

0.017

 RNA_SPLICING

87

1.82

0.020

 REACTOME_MRNA_SPLICING

104

1.80

0.023

 REACTOME_CELL_CYCLE

328

1.79

0.024

 REACTOME_CELL_CYCLE_CHECKPOINTS

97

1.78

0.026

 CELLULAR_COMPONENT_ASSEMBLY

272

1.75

0.030

 REGULATION_OF_TRANSCRIPTION_FROM_RNA_POLYMERASE_II_PROMOTER

271

1.75

0.030

 MRNA_METABOLIC_PROCESS

78

1.74

0.031

 REACTOME_HIV_INFECTION

183

1.74

0.031

 RANSCRIPTION_FROM_RNA_POLYMERASE_II_PROMOTER

427

1.73

0.032

 REACTOME_SIGNALING_BY_BMP

21

1.72

0.032

 REACTOME_TRANSCRIPTIONAL_ACTIVITY_OF_SMAD2_SMAD3_SMAD4_HETEROTRIMER

33

1.72

0.033

 REACTOME_ACTIVATION_OF_THE_MRNA_UPON_BINDING_OF_THE_CAP_BINDING_COMPLEX_AND_EIFS_AND_SUBSEQUENT_BINDING_TO_43S

56

1.71

0.034

 REACTOME_SIGNALING_BY_TGF_BETA_RECEPTOR_COMPLEX

56

1.70

0.037

 REACTOME_CELL_CYCLE_MITOTIC

255

1.70

0.037

 NUCLEAR_EXPORT

31

1.68

0.041

 REACTOME_DOWNREGULATION_OF_SMAD2_3_SMAD4_TRANSCRIPTIONAL_ACTIVITY

18

1.68

0.041

 POSITIVE_REGULATION_OF_NUCLEOBASENUCLEOSIDENUCLEOTIDE_AND_NUCLEIC_ACID_METABOLIC_PROCESS

143

1.68

0.042

 KEGG_RNA_DEGRADATION

55

1.67

0.042

 KEGG_ADHERENS_JUNCTION

70

1.67

0.043

 G1_S_TRANSITION_OF_MITOTIC_CELL_CYCLE

25

1.67

0.045

 REACTOME_TRANSPORT_OF_MATURE_TRANSCRIPT_TO_CYTOPLASM

51

1.66

0.045

 POSITIVE_REGULATION_OF_TRANSCRIPTION

134

1.65

0.048

 None