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Fig. 3 | Breast Cancer Research

Fig. 3

From: Alcohol consumption and breast tumor gene expression

Fig. 3

a, b Replicated enriched pathway-defined gene sets (false discovery rate (FDR) <0.1) by alcohol consumption in the Nurses’ Health Study (NHS) and the NHSII. Replicated significantly enriched gene sets according to recent alcohol intake (i.e. 10+ vs. 0 g/day) in estrogen receptor (ER)+ tumors and the same gene sets in tumor-adjacent normal tissues (a), and in ER- tumors and the same gene sets in tumor-adjacent normal tissues (b), NHSI/II. The primary biological processes observed are shown: N = 19 and 38 gene sets for ER+ and ER- tumors, respectively; -log10(FDR)*direction: red indicates upregulation and blue downregulation

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