Characteristic | Value | Â |
---|---|---|
Number of included patients | 46 | Â |
Age, mean (range), years | 54 (33–72) |  |
Postmenopausal, n (%) | 20 | 43 |
Histological assessment, n (%) | ||
 Invasive ductal carcinoma | 40 | 87 |
 Invasive lobular carcinoma | 4 | 9 |
 Metaplastic carcinoma | 2 | 4 |
TNM stage at diagnosis, n (%) | ||
 T2N0 | 13 | 28 |
 T2N+ | 17 | 37 |
 T3N0 | 5 | 11 |
 T3N+ | 9 | 20 |
 T4N+ | 2 | 4 |
Molecular characteristics, n (%) | ||
 Luminal A | 3 | 6 |
 Luminal B | 16 | 35 |
 Luminal B HER2+ | 6 | 13 |
 HER2+ | 9 | 20 |
 Triple negative | 12 | 26 |
Histopathological response to NAC in surgical specimen (RECIST 1.1), n (%) | Â | Â |
 Complete response (pCR) | 8 | 17 |
 Partial response (pPR) | 32 | 70 |
 Stable disease (pSD) | 5 | 11 |
 Progressive disease (pPD) | 1 | 2 |
Surgical treatment, n (%) | ||
 Lumpectomy | 28 | 61 |
 Mastectomy | 18 | 39 |