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Fig. 4 | Breast Cancer Research

Fig. 4

From: Contrast-enhanced spectral mammography in neoadjuvant chemotherapy monitoring: a comparison with breast magnetic resonance imaging

Fig. 4

Partial response in invasive ductal carcinoma (IDC) and ductal carcinoma in situ (DCIS) component with microcalcifications. Partial response to neoadjuvant chemotherapy (NAC) in a 45-year-old woman with 50 mm in situ and IDC (G3, luminal B) in the left breast, correctly assessed using contrast-enhance spectral mammography (CESM) (a, d, g magnification of craniocaudal (CC) low-dose image; b, e, h magnification of CC recombined image) and magnetic resonance imaging (MRI) (c, f, i axial maximum intensity projection reconstruction). Pre-NAC, evaluation (a, b, c) showed the presence of microcalcifications (a) in the context of the enhancing tumor bed on CESM (b). MRI revealed 50 mm of malignant enhancement (c). During-NAC (d, e, f), both on CESM (d, e) and on MRI (f) we identified progressive disease with the comparison of a second satellite lesion (arrow). Post NAC (g, h, i), multiple foci of residual enhancement scattered inside the tumor bed were visible on CESM (g, h) and MRI (i). Partial response was confirmed by histopathological examination of the surgical specimen

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